Hematopoietic Stem Cell Transplant for Mycosis Fungoides and Sézary Syndrome. Review uri icon

Overview

abstract

  • Mycosis fungoides (MF) and Sézary syndrome (SS) are common types of primary cutaneous T-cell lymphoma. Early-stage MF has a favorable prognosis and responds well to skin-directed regimens. Patients with advanced-stage MF, transformed MF, and SS are treated with combined systemic and skin-directed therapies. However, the disease is incurable with standard regimens, and frequent relapses are common. Owing to the lack of improvement in overall survival with standard regimens, hematopoietic stem cell transplant (HSCT) has been explored as a potential curative option. This article reviews the role of HSCT in MF/SS and discusses data regarding conditioning regimens, treatment-related complications, and outcomes.

publication date

  • July 29, 2015

Research

keywords

  • Hematopoietic Stem Cell Transplantation
  • Mycosis Fungoides
  • Sezary Syndrome
  • Skin Neoplasms

Identity

Scopus Document Identifier

  • 84942817572

Digital Object Identifier (DOI)

  • 10.1016/j.det.2015.05.014

PubMed ID

  • 26433851

Additional Document Info

volume

  • 33

issue

  • 4