How May Proton Pump Inhibitors Impair Cardiovascular Health? Review uri icon

Overview

abstract

  • Proton pump inhibitors (PPIs) are among the most widely used drugs worldwide. They are used to treat a number of gastroesophageal disorders and are usually prescribed as a long-term medication or even taken without a prescription. There are a number of clinical studies that associate PPI use with an increased cardiovascular risk. In this article, we review the clinical evidence for adverse cardiovascular effects of PPIs, and we discuss possible biological mechanisms by which PPIs can impair cardiovascular health.

publication date

  • June 1, 2016

Research

keywords

  • Cardiovascular Diseases
  • Cardiovascular System
  • Evidence-Based Medicine
  • Models, Cardiovascular
  • Proton Pump Inhibitors

Identity

PubMed Central ID

  • PMC4864131

Scopus Document Identifier

  • 84955579662

Digital Object Identifier (DOI)

  • 10.1007/s40256-016-0160-9

PubMed ID

  • 26817947

Additional Document Info

volume

  • 16

issue

  • 3