Individual risk of abdominal disease in patients with stages I and II supradiaphragmatic Hodgkin's disease. A rule index based on 341 laparotomized patients. Academic Article uri icon

Overview

abstract

  • A multivariate analysis of the prognostic factors for clinical Stages I and II supradiaphragmatic Hodgkin's disease was carried out with a logistic regression model in 341 patients. The proportion of patients with positive staging laparotomy was greater in males, in individuals with several sites involved, mixed cellularity (MC) or lymphocyte depletion (LD) histologic types, systemic symptoms, or in patients with lower cervical involvement and higher erythrocyte sedimentation rate (ESR), serum copper, and LDH levels. Histology, presence of systemic symptoms (fever and sweats), and number of involved nodal regions were independent predictors of positive laparotomy. Mediastinal involvement is correlated to a significantly lower risk of positive laparotomy. Based on these observations, the individual risk for each patient of occult abdominal disease has been defined.

publication date

  • May 1, 1989

Research

keywords

  • Abdominal Neoplasms
  • Hodgkin Disease

Identity

Scopus Document Identifier

  • 0024588249

Digital Object Identifier (DOI)

  • 10.1002/1097-0142(19900501)63:9<1799::aid-cncr2820630923>3.0.co;2-r

PubMed ID

  • 2702587

Additional Document Info

volume

  • 63

issue

  • 9