Acute and delayed bleeding requiring embolization after image-guided liver biopsy in patients with cancer. Academic Article uri icon

Overview

abstract

  • PURPOSE: To report incidence of acute versus delayed presentations of bleeding requiring embolization after focal liver biopsy, in correlation with angiographic findings and treatment success rates. The available literature will be reviewed as well. MATERIALS AND METHODS: Health Insurance Portability and Accountability Act-compliant institutional review board approved retrospective review of 2180 consecutive patients undergoing 2335 targeted liver biopsies at a tertiary-care cancer center. Hepatic arterial embolization episodes within 30days from biopsy were identified via radiology PACS. Electronic medical record review was performed for indication of embolization and postembolization clinical course. RESULTS: The incidence of postbiopsy bleeding requiring embolization was 0.5% (12/2335 biopsies). In those with bleeding, 1/12 (8%) had no hepatic arterial findings at angiography. Angiographic hepatic arterial findings resolved after embolization in 11/11 patients (100% technical success). Bleeding ceased after embolization in 10/12 patients (83% clinical success). Complications were seen in 2/12 (17%) patients: cholecystitis and hepatic infarct, respectively. Delayed presentation of bleeding (defined as >24h postbiopsy) occurred in 5/12 (42%) patients; the longest latency was 12days. CONCLUSION: The overall incidence of bleeding requiring embolization in our population was 0.5%. This complication rate compares favorably to the 0-4.2% (median: 0.29%) rate quoted in the available, heterogeneous, literature on this topic. Delayed presentation occurred in almost half of patients. Arterial embolization carries excellent technical and clinical success rates.

publication date

  • November 14, 2015

Research

keywords

  • Embolization, Therapeutic
  • Hemorrhage
  • Image-Guided Biopsy
  • Liver
  • Liver Diseases

Identity

PubMed Central ID

  • PMC9383037

Scopus Document Identifier

  • 84960154118

Digital Object Identifier (DOI)

  • 10.2214/ajr.07.2071

PubMed ID

  • 27133700

Additional Document Info

volume

  • 40

issue

  • 3