IgG4-Related Kidney Disease in a Patient With History of Breast Cancer: Findings on 18F-FDG PET/CT. uri icon

Overview

abstract

  • A 64-year-old African American woman with history of stage III breast carcinoma, 3 years after complete response to therapy, presents with progressive fatigue, increasing arthralgia, and unintentional weight loss of 15 lb in 3 months. An F-FDG PET demonstrated new diffuse FDG avidity of the renal parenchyma, new FDG-avid foci in pancreas and lungs, and new FDG-avid lymph nodes above and below the diaphragm. While a retroperitoneal lymph node biopsy was inconclusive, a kidney biopsy resulted in diagnosis of diffuse, severe, IgG4-related tubulointerstitial nephritis. Treatment with corticosteroid led to complete resolution of the symptoms and PET findings.

publication date

  • August 1, 2016

Research

keywords

  • Autoimmune Diseases
  • Breast Neoplasms
  • Carcinoma
  • Immunoglobulin G
  • Nephritis
  • Positron Emission Tomography Computed Tomography

Identity

PubMed Central ID

  • PMC4977093

Scopus Document Identifier

  • 84969135092

Digital Object Identifier (DOI)

  • 10.1097/RLU.0000000000001252

PubMed ID

  • 27187735

Additional Document Info

volume

  • 41

issue

  • 8