Metabolic control of asyMYCtric division. uri icon

Overview

abstract

  • Asymmetric division in CD8 T cells produces two daughter cells expressing different levels of c-Myc with distinct metabolic profiles. Manipulating this asymmetric partitioning of c-Myc skews T cell responses and potentially allows the development of more effective vaccines and cancer immunotherapies.

publication date

  • May 20, 2016

Research

keywords

  • CD8-Positive T-Lymphocytes

Identity

PubMed Central ID

  • PMC4973327

Scopus Document Identifier

  • 84969715239

Digital Object Identifier (DOI)

  • 10.1038/cr.2016.60

PubMed ID

  • 27197568

Additional Document Info

volume

  • 26

issue

  • 8