Pediatric Malignant Bone Tumors: A Review and Update on Current Challenges, and Emerging Drug Targets. Review uri icon

Overview

abstract

  • Osteosarcoma (OS) and the Ewing sarcoma family of tumors (ESFT) are the most common malignant bone tumors in children and adolescents. While significant improvements in survival have been seen in other pediatric malignancies the treatment and prognosis for pediatric bone tumors has remained unchanged for the past 3 decades. This review and update of pediatric malignant bone tumors will provide a general overview of osteosarcoma and the Ewing sarcoma family of tumors, discuss bone tumor genomics, current challenges, and emerging drug targets.

publication date

  • June 2, 2016

Research

keywords

  • Bone Neoplasms
  • Osteosarcoma

Identity

Scopus Document Identifier

  • 84975266413

Digital Object Identifier (DOI)

  • 10.1016/j.cppeds.2016.04.002

PubMed ID

  • 27265835

Additional Document Info

volume

  • 46

issue

  • 7