Prevention of breast cancer by RANKL/RANK blockade. uri icon

Overview

abstract

  • Robust genetic evidence in mice and humans indicates that RANK signaling plays a major role in mammary carcinogenesis driven by BRCA1/BRCA2 mutations. These findings may inaugurate a new era of breast cancer prevention, changing the life of millions of women worldwide.

publication date

  • June 21, 2016

Research

keywords

  • Breast Neoplasms

Identity

PubMed Central ID

  • PMC5129887

Scopus Document Identifier

  • 84975510092

Digital Object Identifier (DOI)

  • 10.1038/cr.2016.79

PubMed ID

  • 27325297

Additional Document Info

volume

  • 26

issue

  • 7