Evaluation and management of the swollen optic disk in cryptococcal meningitis. Review uri icon

Overview

abstract

  • Cryptococcal meningitis is the most common and severe form of cryptococcal infection. In addition to infiltrative and inflammatory mechanisms, intracranial hypertension commonly complicates cryptococcal meningitis and may cause significant visual and neurological morbidity and mortality. The mainstays of treatment for cryptococcal meningitis include standard antifungal therapy, management of intracranial hypertension, and treatment of underlying immunosuppressive conditions. Early and aggressive management of intracranial hypertension in accordance with established guidelines reduces the risk of long-term visual and neurological complications and death. Traditional recommendations for treating elevated intracranial pressure in idiopathic intracranial hypertension including acetazolamide, weight loss, and avoiding serial lumbar punctures-are not helpful in cryptococcal meningitis and may be harmful.

publication date

  • October 15, 2016

Research

keywords

  • Antifungal Agents
  • Disease Management
  • Meningitis, Cryptococcal
  • Optic Disk
  • Papilledema
  • Spinal Puncture

Identity

Scopus Document Identifier

  • 85007448400

Digital Object Identifier (DOI)

  • 10.1016/j.survophthal.2016.10.004

PubMed ID

  • 27751821

Additional Document Info

volume

  • 62

issue

  • 2