Kidney volume and ambulatory blood pressure in children. Academic Article uri icon

Overview

abstract

  • Low nephron number has been shown to be a risk factor for hypertension (HTN) in adulthood. Kidney volume may serve as a surrogate marker for nephron mass. The relationship between kidney volume and ambulatory blood pressure (BP) in the pediatric population is not known. A retrospective chart review of children younger than 21 years who were evaluated for HTN was performed. Twenty-four-hour BP and ultrasonography data were obtained. Multiple regression was used to examine associations between BP and kidney volume. Of 84 children (mean age 13.87 years, 72.6% males), 54 had HTN. Systolic BP index during the awake, sleep, and 24-hour periods (all P≤.05) was found to be positively correlated with total kidney volume. Greater total kidney volume was found to be a positive predictor of 24-hour and sleep systolic index (P≤.05). It failed to serve as a predictor of HTN, pre-HTN, or white-coat HTN. Contrary to expectation, total kidney volume was positively associated with systolic BP indices.

publication date

  • December 16, 2016

Research

keywords

  • Blood Pressure
  • Blood Pressure Monitoring, Ambulatory
  • Hypertension
  • Kidney
  • Nephrons

Identity

PubMed Central ID

  • PMC8031291

Scopus Document Identifier

  • 85006856369

Digital Object Identifier (DOI)

  • 10.1111/jch.12954

PubMed ID

  • 27982509

Additional Document Info

volume

  • 19

issue

  • 5