Bidentate iminodiacetate modified dendrimer for bone imaging. Academic Article uri icon

Overview

abstract

  • A new dendrimer probe was designed for bone imaging. Bidentate iminodiacetate groups were introduced to the probe to obtain strong bind to bones. The assembled dendrimeric probe, with four iminodiacetate moieties and a fluorescent tag, displayed good selectivity to hydroxyapatite, calcium oxalate and calcium phosphate salts. In mice, the probe offered vivid skeletal details after intravenous delivery.

publication date

  • January 20, 2017

Research

keywords

  • Bone and Bones
  • Dendrimers
  • Diagnostic Imaging
  • Fluorescent Dyes
  • Imino Acids
  • Polylysine

Identity

PubMed Central ID

  • PMC5328641

Scopus Document Identifier

  • 85011000780

Digital Object Identifier (DOI)

  • 10.1016/j.bmcl.2017.01.059

PubMed ID

  • 28153357

Additional Document Info

volume

  • 27

issue

  • 5