Neuropathy and IgM paraproteinemia: differential binding of IgM M-proteins to peripheral nerve glycolipids. uri icon

Overview

abstract

  • Two patients with neuropathy and IgM paraproteinemia displayed different immunoreactivity to acidic peripheral nerve glycolipids. In one patient, immunostaining on thin-layer chromatographic plate revealed binding of the IgM to sulfated glucuronosyl paragloboside (SGPG) and sulfated glucuronosyl lactosaminyl paragloboside (SGLPG). The other IgM bound SGPG, SGLPG, and a new third glycolipid. Immunoreactivity of the IgM varies in this syndrome.

publication date

  • November 1, 1987

Research

keywords

  • Glycolipids
  • Immunoglobulin M
  • Paraproteinemias
  • Peripheral Nervous System Diseases

Identity

Scopus Document Identifier

  • 0023626457

Digital Object Identifier (DOI)

  • 10.1212/wnl.37.11.1795

PubMed ID

  • 2823182

Additional Document Info

volume

  • 37

issue

  • 11