Practical Considerations of Fractional Flow Reserve Utilization to Guide Revascularization. Review uri icon

Overview

abstract

  • Invasive angiography has long been the gold standard for the diagnosis of obstructive coronary artery disease (CAD). However, the relationship between angiographic measures of stenosis and coronary blood flow is complex, and there is frequent discordance between the visual assessment of a stenotic lesion and its effect on myocardial perfusion. Fractional flow reserve is a rapidly emerging invasive means of assessing the physiologic significance of an epicardial stenosis. This review provides a pragmatic understanding of the physiologic principles that guide fractional flow reserve (FFR), sheds light on its nuances, and explores the most landmark investigations. We will also discuss how the measurement of FFR can be helpful or limiting in several common clinical situations.

publication date

  • February 1, 2017

Identity

Scopus Document Identifier

  • 85014857673

Digital Object Identifier (DOI)

  • 10.1007/s11936-017-0514-x

PubMed ID

  • 28281238

Additional Document Info

volume

  • 19

issue

  • 2