Enabling Task-Specific Volitional Motor Functions via Spinal Cord Neuromodulation in a Human With Paraplegia. uri icon

Overview

abstract

  • We report a case of chronic traumatic paraplegia in which epidural electrical stimulation (EES) of the lumbosacral spinal cord enabled (1) volitional control of task-specific muscle activity, (2) volitional control of rhythmic muscle activity to produce steplike movements while side-lying, (3) independent standing, and (4) while in a vertical position with body weight partially supported, voluntary control of steplike movements and rhythmic muscle activity. This is the first time that the application of EES enabled all of these tasks in the same patient within the first 2 weeks (8 stimulation sessions total) of EES therapy.

authors

  • Grahn, Peter J
  • Lavrov, Igor A
  • Sayenko, Dimitry
  • Van Straaten, Meegan G
  • Gill, Megan L
  • Strommen, Jeffrey A
  • Calvert, Jonathan S
  • Drubach, Dina I
  • Beck, Lisa A
  • Linde, Margaux B
  • Thoreson, Andrew R
  • Lopez, Cesar
  • Mendez, Aldo A
  • Gad, Parag N
  • Gerasimenko, Yury P
  • Edgerton, V Reggie
  • Zhao, Kristin D
  • Lee, Kendall H

publication date

  • April 1, 2017

Research

keywords

  • Electric Stimulation Therapy
  • Muscle, Skeletal
  • Paraplegia
  • Spinal Cord
  • Spinal Cord Injuries

Identity

Scopus Document Identifier

  • 85016990518

Digital Object Identifier (DOI)

  • 10.1016/j.mayocp.2017.02.014

PubMed ID

  • 28385196

Additional Document Info

volume

  • 92

issue

  • 4