Latent herpes simplex virus type 1 transcription in human trigeminal ganglia. Academic Article uri icon

Overview

abstract

  • We studied latent herpes simplex virus type 1 gene expression in human trigeminal ganglia. Two transcripts were mapped to a 3.0-kilobase region within the long repeat region and appeared to be located in neuronal nuclei. These viral RNAs were not abundant during lytic replication and may represent an alternative pattern of herpes simplex virus type 1 gene expression involved in the pathogenesis of latent infection.

publication date

  • September 1, 1988

Research

keywords

  • Gene Expression Regulation
  • Herpes Simplex
  • Simplexvirus
  • Transcription, Genetic
  • Trigeminal Ganglion
  • Trigeminal Nerve

Identity

PubMed Central ID

  • PMC253475

Scopus Document Identifier

  • 0023793212

Digital Object Identifier (DOI)

  • 10.1128/JVI.62.9.3493-3496.1988

PubMed ID

  • 2841498

Additional Document Info

volume

  • 62

issue

  • 9