Treatment of cytomegalovirus retinitis with ganciclovir (9-[2-hydroxy-1-(hydroxymethyl) ethoxymethyl] guanine (BW B759U). Academic Article uri icon

Overview

abstract

  • Six patients (11 eyes) with virologically confirmed cytomegalovirus (CMV) retinitis involving the posterior pole of the eye were treated with a new drug, ganciclovir. Treatment with intravenous ganciclovir consistently halted progression of retinitis and produced improvement in measures of visual function. However, within three weeks after cessation of therapy renewed CMV activity and worsening of visual function were observed in most cases. Maintenance therapy with ganciclovir extended the period of remission from CMV retinitis.

publication date

  • July 1, 1988

Research

keywords

  • Acyclovir
  • Antiviral Agents
  • Cytomegalovirus Infections
  • Retinitis

Identity

PubMed Central ID

  • PMC1041518

Scopus Document Identifier

  • 0023727138

Digital Object Identifier (DOI)

  • 10.1136/bjo.72.7.525

PubMed ID

  • 2843219

Additional Document Info

volume

  • 72

issue

  • 7