Modulation of postjunctional alpha-adrenergic responsiveness by local changes in temperature. Academic Article uri icon

Overview

abstract

  • In canine cutaneous veins, local moderate warming (37 degrees-41 degrees C) augments the responsiveness to postjunctional alpha 1-adrenergic stimulation but depresses that to postjunctional alpha 2-adrenergic activation. Moderate cooling (37 degrees-24 degrees C) has the opposite effect. The effects of warming and cooling on alpha 1-adrenergic responses are buffered by a large receptor reserve, allowing for the predominance of alterations in alpha 2-adrenergic responsiveness.

publication date

  • January 1, 1985

Research

keywords

  • Adrenergic alpha-Agonists
  • Receptors, Adrenergic, alpha
  • Temperature

Identity

Scopus Document Identifier

  • 0021911566

Digital Object Identifier (DOI)

  • 10.1042/cs068s121

PubMed ID

  • 2857606

Additional Document Info

volume

  • 68 Suppl 10