Autologous Chondrocytes and Next-Generation Matrix-Based Autologous Chondrocyte Implantation. Review uri icon

Overview

abstract

  • Focal chondral defects of the knee are common and can significantly impair quality of life. The autologous chondrocyte implantation technique has evolved over the past 20 years; the newest third-generation technique is matrix-induced autologous chondrocyte implantation. Physical examination is important to characterize location and source of pain and identify associated injuries. Imaging studies allow characterization of the lesions, identification of associated lesions, and alignment. Conservative measures should be exhausted before proceeding with surgical treatment. Steps of surgical treatment are diagnostic arthroscopy and biopsy, chondrocyte culture, and chondrocyte implantation. The techniques and their outcomes are discussed in this article.

publication date

  • July 1, 2017

Research

keywords

  • Cartilage Diseases
  • Cartilage, Articular
  • Chondrocytes
  • Knee Injuries

Identity

Scopus Document Identifier

  • 85020431972

Digital Object Identifier (DOI)

  • 10.1016/j.csm.2017.02.008

PubMed ID

  • 28577711

Additional Document Info

volume

  • 36

issue

  • 3