Effects of dehydration on pro-dynorphin derived peptides in the neuro-intermediate lobe of the rat pituitary. Academic Article uri icon

Overview

abstract

  • Dehydration significantly reduced the concentration of immunoreactive dynorphin A(1-17), dynorphin A(1-8), alpha-neo-endorphin, beta-neo-endorphin, and leu-enkephalin in the rat pituitary posterior-intermediate lobe. A statistically significant increase in immunoreactive dynorphin A(1-8), alpha-neo-endorphin and leu-enkephalin was observed in the hypothalamus. Comparison of the molar ratios of dynorphin A(1-17): dynorphin A(1-8) and alpha-neo-endorphin: beta-neo-endorphin showed an altered profile of stored pro-dynorphin cleavage products in the posterior-intermediate lobe of the pituitary of dehydrated rats.

publication date

  • October 21, 1985

Research

keywords

  • Dehydration
  • Enkephalins
  • Pituitary Gland, Posterior
  • Protein Precursors
  • beta-Endorphin

Identity

Scopus Document Identifier

  • 0022000859

Digital Object Identifier (DOI)

  • 10.1016/0024-3205(85)90184-5

PubMed ID

  • 2864623

Additional Document Info

volume

  • 37

issue

  • 16