SWI/SNF tumor suppressor gene PBRM1/BAF180 in human clear cell kidney cancer. Academic Article uri icon

Overview

abstract

  • Mutations within chromatin modulating protein complexes have dominated the novel cancer gene landscape. However, little is known about how individual aberrations contribute to cancer formation. A novel Pbrm1 kidney cancer mouse model examining the role of Pbrm1 provides much needed clue concerning how SWI/SNF complexes might function as tumor suppressors.

publication date

  • June 19, 2017

Identity

PubMed Central ID

  • PMC5540208

Scopus Document Identifier

  • 85044262134

Digital Object Identifier (DOI)

  • 10.1016/j.eururo.2016.10.007

PubMed ID

  • 28868352

Additional Document Info

volume

  • 4

issue

  • 4