What Is the Role of α-Blockers for Medical Expulsive Therapy? Results From a Meta-analysis of 60 Randomized Trials and Over 9500 Patients. Review uri icon

Overview

abstract

  • Use of α-blockers for medical expulsive therapy (MET) has been the subject of huge debate in urology. Moreover, there have been a number of randomized controlled trials with differing results. We conducted a systematic review and meta-analysis of randomized controlled trials investigating the efficacy of α-blockers for MET. This review confirms there is a role for α-blockers in MET for ureteric stones specifically in stones >5 mm and distal ureteric stones, which is associated with improved stone expulsion. However, there is a slight increase in risk of nonsignificant side effects.

publication date

  • April 4, 2018

Research

keywords

  • Adrenergic alpha-Antagonists
  • Ureteral Calculi

Identity

Scopus Document Identifier

  • 85046644580

Digital Object Identifier (DOI)

  • 10.1016/j.urology.2018.03.028

PubMed ID

  • 29626570

Additional Document Info

volume

  • 119