Hypertension Induced Morphological and Physiological Changes in Cells of the Arterial Wall. Review uri icon

Overview

abstract

  • Morphological and physiological changes in the vasculature have been described in the evolution and maintenance of hypertension. Hypertension-induced vascular dysfunction may present itself as a contributing, or consequential factor, to vascular remodeling caused by chronically elevated systemic arterial blood pressure. Changes in all vessel layers, from the endothelium to the perivascular adipose tissue (PVAT), have been described. This mini-review focuses on the current knowledge of the structure and function of the vessel layers, specifically muscular arteries: intima, media, adventitia, PVAT, and the cell types harbored within each vessel layer. The contributions of each cell type to vessel homeostasis and pathophysiological development of hypertension will be highlighted.

publication date

  • September 11, 2018

Research

keywords

  • Arterial Pressure
  • Arteries
  • Hypertension
  • Vascular Remodeling

Identity

PubMed Central ID

  • PMC6132119

Scopus Document Identifier

  • 85053816556

Digital Object Identifier (DOI)

  • 10.1093/ajh/hpy083

PubMed ID

  • 29788246

Additional Document Info

volume

  • 31

issue

  • 10