Using LICHeE and BAMSE for Reconstructing Cancer Phylogenetic Trees. Academic Article uri icon

Overview

abstract

  • The reconstruction of cancer phylogeny trees and quantifying the evolution of the disease is a challenging task. LICHeE and BAMSE are two computational tools designed and implemented recently for this purpose. They both utilize estimated variant allele fraction of somatic mutations across multiple samples to infer the most likely cancer phylogenies. This unit provides extensive guidelines for installing and running both LICHeE and BAMSE. © 2018 by John Wiley & Sons, Inc.

publication date

  • May 16, 2018

Research

keywords

  • Algorithms
  • Computational Biology
  • Neoplasms
  • Phylogeny

Identity

PubMed Central ID

  • PMC6020047

Scopus Document Identifier

  • 85054100295

Digital Object Identifier (DOI)

  • 10.1186/s13059-015-0647-8

PubMed ID

  • 29927069

Additional Document Info

volume

  • 62

issue

  • 1