Methodological Issues in Studying PAHSA Biology: Masking PAHSA Effects. uri icon

Overview

abstract

  • PAHSAs are anti-diabetic and anti-inflammatory lipids. Syed et al. identify numerous experimental differences that likely account for the failure of Pflimlin et al. to observe PAHSA beneficial effects. The differences include different HFDs resulting in minimal/no glucose intolerance, different assay conditions, an LC-MS protocol that was not validated, and use of olive oil, a bioactive nutrient that improves glucose tolerance, as a vehicle.

publication date

  • September 20, 2018

Research

keywords

  • Blood Glucose
  • Lipids

Identity

PubMed Central ID

  • PMC6542592

Scopus Document Identifier

  • 85054431556

Digital Object Identifier (DOI)

  • 10.1039/c8lc00624e

PubMed ID

  • 30244974

Additional Document Info

volume

  • 28

issue

  • 4