Virus, Vessel, Victory: A Novel Approach to Tumor Killing. uri icon

Overview

abstract

  • Ovarian cancer is intimately dependent on aberrant tumor vasculature. A unique therapeutic approach combining a systemic oncolytic virus with a novel vascular-normalizing agent in ovarian cancer demonstrates the potential to enhance antitumor efficacy through improved delivery of the virus and enhanced infiltration of immune cells into the tumors.See related article by Matuszewska et al., p. 1624.

publication date

  • December 10, 2018

Research

keywords

  • Oncolytic Virotherapy
  • Oncolytic Viruses
  • Ovarian Neoplasms

Identity

PubMed Central ID

  • PMC6397697

Scopus Document Identifier

  • 85062282382

Digital Object Identifier (DOI)

  • 10.1096/fj.14-261636

PubMed ID

  • 30530816

Additional Document Info

volume

  • 25

issue

  • 5