Challenges in assessing the efficacy of systemic corticosteroids for severe wheezing episodes in preschool children. uri icon

Overview

abstract

  • This letter addresses the controversial issue of the use of oral corticosteroids during wheezing exacerbations in preschool-aged children by demonstrating findings of a prematurely terminated multi-center clinical trial, discussing lessons learned, and suggesting future directions.

authors

  • Permaul, Perdita
  • Guilbert, Theresa W
  • Bacharier, Leonard B
  • Mauger, David T
  • Phipatanakul, Wanda
  • Szefler, Stanley J
  • Boehmer, Susan
  • Beigelman, Avraham
  • Fitzpatrick, Anne M
  • Jackson, Daniel J
  • Baxi, Sachin N
  • Benson, Mindy
  • Burnham, Carey-Ann D
  • Cabana, Michael D
  • Castro, Mario
  • Chmiel, James F
  • Covar, Ronina
  • Daines, Michael
  • Gaffin, Jonathan M
  • Gentile, Deborah A
  • Holguin, Fernando
  • Israel, Elliot
  • Kelly, H William
  • Lazarus, Stephen C
  • Lemanske, Robert F
  • Ly, Ngoc
  • Meade, Kelley
  • Morgan, Wayne
  • Moy, James
  • Olin, J Tod
  • Peters, Stephen P
  • Pongracic, Jacqueline A
  • Raissy, Hengameh H
  • Ross, Kristie
  • Sheehan, William J
  • Sorkness, Christine
  • Teague, W Gerald
  • Thyne, Shannon
  • Martinez, Fernando D

publication date

  • January 17, 2019

Research

keywords

  • Asthma
  • Respiratory Sounds

Identity

PubMed Central ID

  • PMC6504562

Scopus Document Identifier

  • 85061157615

Digital Object Identifier (DOI)

  • 10.1016/j.jaci.2018.10.071

PubMed ID

  • 30660645

Additional Document Info

volume

  • 143

issue

  • 5