How to Treat a Patient with T1 High-grade Disease and No Tumour on Repeat Transurethral Resection of the Bladder? Academic Article uri icon

Overview

abstract

  • A relatively young (64-yr old) long-term heavy smoker but otherwise very healthy man is diagnosed with a primary unifocal left-side tumour (urothelial, T1 high grade), but no lymphovascular invasion and no variant histology. We discuss whether treatment with intravesical bacillus Calmette-Guérin vaccine will be sufficient or early radical cystectomy is at least equally preferred regarding patient benefit, safety, and quality of life. PATIENT SUMMARY: A patient with a single high-grade T1 bladder tumour without aggressive features (eg, lymphovascular invasion or variant tumour aspects) will be adequately treated with bacillus Calmette-Guérin intravesical therapy delivered into the bladder, followed by 3 yr of maintenance. However, all decisions should be taken with the patient in a shared decision-making process, including a discussion regarding removal of the bladder.

publication date

  • September 1, 2019

Research

keywords

  • Urinary Bladder
  • Urinary Bladder Neoplasms

Identity

Scopus Document Identifier

  • 85114120246

Digital Object Identifier (DOI)

  • 10.1016/j.euo.2019.07.006

PubMed ID

  • 31481345

Additional Document Info

volume

  • 4

issue

  • 4