Neuronal regulation of group 2 innate lymphoid cells and type 2 inflammation. Review uri icon

Overview

abstract

  • Diverse infectious, inflammatory, and environmental stimuli induce type 2 inflammation in the body. Group 2 innate lymphoid cells (ILC2s) are potent producers of type 2 cytokines and play important roles in promoting type 2 inflammation. In addition to alarmins and other cytokines which are known to regulate ILC2 responses, emerging studies identified the regulation of ILC2s by the nervous system through neurotransmitter and neuropeptides. In this review, we highlight recent advances in the regulation of ILC2s and type 2 inflammation by the nervous system.

publication date

  • September 16, 2019

Research

keywords

  • Cytokines
  • Immunity, Innate
  • Inflammation
  • Lymphocytes
  • Neuroimmunomodulation
  • Neurons
  • Neuropeptides

Identity

Scopus Document Identifier

  • 85072184135

Digital Object Identifier (DOI)

  • 10.1016/bs.ai.2019.08.001

PubMed ID

  • 31607366

Additional Document Info

volume

  • 143