TNFα Blockade in Checkpoint Inhibition: The Good, the Bad, or the Ugly? uri icon

Overview

abstract

  • The impact on survival of steroids and TNFα blockade to treat immune-related toxicity from checkpoint blockade with ipilimumab, nivolumab/pembrolizumab, or combined ipilimumab and nivolumab was assessed using data from a large national database. Using steroids was associated with better survival than the use of TNFα-blocking antibodies such as infliximab.See related article by Verheijden et al., p. 2268.

publication date

  • February 26, 2020

Research

keywords

  • Melanoma
  • Tumor Necrosis Factor-alpha

Identity

Scopus Document Identifier

  • 85084961524

Digital Object Identifier (DOI)

  • 10.1158/1078-0432.CCR-20-0387

PubMed ID

  • 32102949

Additional Document Info

volume

  • 26

issue

  • 9