Planning mantle radiation therapy in patients with Hodgkin disease: role of gallium-67 scintigraphy. Academic Article uri icon

Overview

abstract

  • Detection of all sites of lymphoma is imperative for accurate planning of radiation therapy. In patients with Hodgkin disease, mantle radiation is used to treat the thoracic lymph nodes; in those with early-stage or nonbulky disease, mantle and paraaortic radiation may be the only treatment given. CT scanning of the chest adds important information to that obtained from chest radiographs. Gallium-67 scintigraphy has also been used to provide additional information on sites of active tumor. To determine the usefulness of 67Ga-citrate scintigraphy in planning the portals for radiation therapy, we analyzed the radiation treatment plans in 26 consecutive patients with Hodgkin disease; in all 26 patients, the disease had been staged by chest radiographs, chest CT scans, and gallium-67 images. Gallium-67 imaging alone provided unique information that affected the treatment plans in three patients (12%). The combined results of gallium-67 imaging and CT scans influenced the planning of radiation therapy in eight patients (31%). Gallium-67 imaging was found to be an important adjunctive study for optimal planning of radiation therapy in patients with Hodgkin disease.

publication date

  • December 1, 1988

Research

keywords

  • Gallium Radioisotopes
  • Hodgkin Disease

Identity

Scopus Document Identifier

  • 0023738113

Digital Object Identifier (DOI)

  • 10.2214/ajr.151.6.1229

PubMed ID

  • 3263777

Additional Document Info

volume

  • 151

issue

  • 6