Opioid use disorder and maternal outcomes following cesarean delivery: a multistate analysis, 2007-2014. Academic Article uri icon

Overview

abstract

  • Aim: To examine the association between opioid use disorder (OUD) and maternal outcomes following cesarean delivery. Methods: Retrospective analysis of over 2.4 million discharge records for in-patient cesarean delivery across five states from 2007 to 2014. Primary outcome was in-hospital mortality. Secondary outcomes included length of stay (LOS) and 30- and 90-day readmission rates. Results: OUD patients were 148% more likely than non-OUD patients to die during hospitalization (adjusted odds ratios [aOR]: 2.48, 95% CI: 1.20, 5.10; p < 0.05). OUD was associated with increased odds of 30-day readmission (aOR: 1.46, 95% CI: 1.30, 1.65; p < 0.001) and 90-day readmission (aOR: 1.70, 95% CI: 1.55, 1.88; p < 0.001); LOS was not significantly different. Conclusion: OUD predicts increased in-patient mortality and odds of 30- and 90-day readmission following cesarean delivery.

publication date

  • July 10, 2020

Research

keywords

  • Analgesics, Opioid
  • Cesarean Section
  • Hospitalization
  • Maternal Mortality
  • Opioid-Related Disorders
  • Pregnancy Complications

Identity

Scopus Document Identifier

  • 85089204467

Digital Object Identifier (DOI)

  • 10.2217/cer-2020-0050

PubMed ID

  • 32648478

Additional Document Info

volume

  • 9

issue

  • 10