NK cells beat T cells at early breast cancer control. Editorial Article uri icon

Overview

abstract

  • Cancer immunosurveillance generally relies on adaptive immune programs executed by CD8+ T cells. Our findings demonstrate that CD8+ T cells fail to control early oncogenesis in a mouse model of luminal B breast cancer and suggest that natural killer (NK) cells may instead play a predominant role in this setting.

publication date

  • August 23, 2020

Research

keywords

  • CD8-Positive T-Lymphocytes
  • Neoplasms

Identity

PubMed Central ID

  • PMC7458610

Scopus Document Identifier

  • 85089751355

Digital Object Identifier (DOI)

  • 10.1016/j.cell.2018.10.014

PubMed ID

  • 32923169

Additional Document Info

volume

  • 9

issue

  • 1