Chronic recurrent multifocal osteomyelitis: diagnosis and treatment. Review uri icon

Overview

abstract

  • PURPOSE OF REVIEW: The aim of this article is to review recent findings regarding the diagnosis and treatment of chronic recurrent multifocal osteomyelitis (CRMO). RECENT FINDINGS: An adequate understanding of pathophysiology along with the new advances in MRI imaging make it possible to determine the extent of disease and establish early treatment. TNF-α inhibitors and bisphosphonates have shown to be a well-tolerated and efficient treatment for CRMO providing both symptomatic relief and normalization of bone morphology. SUMMARY: The results of recent studies suggest that a better knowledge of the genetic and molecular factors will allow early diagnosis and the development of more effective individualized treatments in the future.

publication date

  • February 1, 2021

Research

keywords

  • Osteomyelitis

Identity

Scopus Document Identifier

  • 85099324850

Digital Object Identifier (DOI)

  • 10.1186/s12969-019-0351-4

PubMed ID

  • 33278106

Additional Document Info

volume

  • 33

issue

  • 1