Seronegative myasthenia gravis. Academic Article uri icon

Overview

abstract

  • Of 221 patients with myasthenia gravis, 18.5% had no detectable antibodies to acetylcholine receptor. Seven of 14 patients (50%) with only ocular symptoms for more than 2 years were seronegative, and 25 of 145 (17%) patients with generalized myasthenia were seronegative. The clinical characteristics of seronegative patients did not differ from patients with high antibody titers. No seronegative patient had a thymoma, but that difference did not reach statistical significance. Lack of serum antibodies did not preclude favorable response to thymectomy or plasmapheresis.

publication date

  • April 1, 1988

Research

keywords

  • Antibodies
  • Myasthenia Gravis

Identity

Scopus Document Identifier

  • 0023878232

Digital Object Identifier (DOI)

  • 10.1212/wnl.38.4.514

PubMed ID

  • 3352902

Additional Document Info

volume

  • 38

issue

  • 4