Ketosis versus carbotoxicity - metabolism determines the outcome of cancer immunotherapy. Academic Article uri icon

Overview

abstract

  • Carbohydrate-rich diets have been consistently associated with detrimental effects for human health, including diabetes and obesity. Moreover, high glucose levels appear to mediate immunosuppressive effects in preclinical tumor models. Recent data from Ferrere and colleagues point to the intriguing possibility that carbotoxicity may originate from the abolition of ketosis.

publication date

  • January 15, 2021

Identity

PubMed Central ID

  • PMC7849725

Scopus Document Identifier

  • 85099463383

Digital Object Identifier (DOI)

  • 10.1172/jci.insight.145207

PubMed ID

  • 33553614

Additional Document Info

volume

  • 8

issue

  • 1