Isomers of 10-hydroxynortriptyline in geriatric depression. Academic Article uri icon

Overview

abstract

  • In geriatric, depressed inpatients treated with nortriptyline (NT), total unconjugated plasma concentrations of the Z isomer of the 10-hydroxylated metabolite (10-OH-NT) were determined simultaneously with concentrations of the E isomer by high-performance liquid chromatography. Z-10-OH-NT concentrations averaged 14% of E-10-OH-NT concentrations.

publication date

  • January 1, 1988

Research

keywords

  • Depressive Disorder
  • Nortriptyline

Identity

Scopus Document Identifier

  • 0023909655

Digital Object Identifier (DOI)

  • 10.1097/00007691-198802000-00008

PubMed ID

  • 3381232

Additional Document Info

volume

  • 10

issue

  • 2