Incidence of hip fractures in osteoporotic women treated with sodium fluoride. Academic Article uri icon

Overview

abstract

  • It has been suggested recently that, although fluoride therapy may decrease the occurrence of vertebral fractures, it could increase the risk of hip fractures. To evaluate this possibility, we combined retrospective data from five medical centers that have had a large experience with this therapeutic regimen. In 416 osteoporotic patients who were followed for more than 1,000 patient-years of fluoride treatment, there were 17 nontraumatic hip fractures. This incidence of 1.6% per year is similar to the incidence, 1.9% per year, for 120 of the patients in this series who had been followed prospectively for 3 years prior to initiation of fluoride therapy. The expected incidence for women of the same age in the general community is 0.5% per year. Thus, untreated osteoporotic women are at increased risk for hip fracture, but treatment with fluoride seems neither to decrease nor to increase the incidence of hip fracture substantially.

publication date

  • April 1, 1987

Research

keywords

  • Hip Fractures
  • Osteoporosis
  • Sodium Fluoride

Identity

Scopus Document Identifier

  • 0023318391

Digital Object Identifier (DOI)

  • 10.1002/jbmr.5650020207

PubMed ID

  • 3455161

Additional Document Info

volume

  • 2

issue

  • 2