Decomposing the mutational landscape of cancer genomes with RepairSig. uri icon

Overview

abstract

  • Mutational signatures are the outcomes of mutagenic processes that occur prior to, and during, tumorigenesis as a result of DNA damage, DNA repair, and DNA replication. In this issue of Cell Systems, Wojtowicz et al. introduce a new computational model aimed at deconstructing the mutational processes that shape cancer genomes.

publication date

  • October 20, 2021

Research

keywords

  • Neoplasms

Identity

Scopus Document Identifier

  • 85120579599

Digital Object Identifier (DOI)

  • 10.1016/j.cels.2021.09.009

PubMed ID

  • 34672958

Additional Document Info

volume

  • 12

issue

  • 10