Immunostimulatory effects of radioimmunotherapy. Academic Article uri icon

Overview

abstract

  • Radiation therapy (RT) is known for its ability to kill cancer cells in an immunogenic manner. Recent preclinical data demonstrate that targeted alpha-particle therapy shares with RT the capacity to elicit immunostimulatory effects, standing out as a promising strategy to circumvent immune checkpoint inhibitor resistance in immunologically 'cold' tumors.

publication date

  • February 1, 2022

Research

keywords

  • Adaptive Immunity
  • Immune Checkpoint Inhibitors
  • Immunization
  • Radioimmunotherapy

Identity

PubMed Central ID

  • PMC8862476

Scopus Document Identifier

  • 85125154090

Digital Object Identifier (DOI)

  • 10.1038/ncomms15618

PubMed ID

  • 35190377

Additional Document Info

volume

  • 10

issue

  • 2