Aspiration pneumonia. Review uri icon

Overview

abstract

  • The growing population of older people worldwide represents a great challenge for health systems. The elderly are at increased risk of infectious diseases such as pneumonia, which is associated with increased morbidity and mortality related mainly to age-related physiological changes in the immune system (immunosenescence), the presence of multiple chronic comorbidities, and frailty. In pneumonia, microaspiration is recognized as the main pathogenic mechanism; while macroaspiration which refers to the aspiration of a large amount of oropharyngeal or upper gastrointestinal content passing through the vocal cords and trachea into the lungs is identified as "aspiration pneumonia". Although there are strategies for the prevention and management of patients with pneumonia that have been shown to be effective in older people with pneumonia, more research is needed on aspiration pneumonia, its risk factors and outcomes, especially since there are no specific criteria for its diagnosis and consequently, the studies on aspiration pneumonia include heterogeneous populations.

publication date

  • April 22, 2022

Research

keywords

  • Pneumonia
  • Pneumonia, Aspiration

Identity

PubMed Central ID

  • PMC9106188

Scopus Document Identifier

  • 85129155747

Digital Object Identifier (DOI)

  • 10.1038/srep38097

PubMed ID

  • 35488832

Additional Document Info

volume

  • 35 Suppl 1

issue

  • Suppl 1