Brachytherapy for central nervous system tumors. Review uri icon

Overview

abstract

  • Radiation is a mainstay of treatment for central nervous system (CNS) tumors. Brachytherapy involves the placement of a localized/interstitial radiation source into a tumor or resection bed and has distinct advantages that can make it an attractive form of radiation when used in the appropriate setting. However, the data supporting use of brachytherapy is clouded by variability in radiation sources, techniques, delivered doses, and trial designs. The goal of this manuscript is to identify consistent themes, review the highest-level evidence and potential indications for brachytherapy in CNS tumors, as well as highlight avenues for future work. Improved understanding of the underlying biology, indications, complications, and evolving industry-academic collaborations, place brachytherapy on the brink of a resurgence.

publication date

  • May 11, 2022

Research

keywords

  • Brachytherapy
  • Brain Neoplasms
  • Central Nervous System Neoplasms
  • Meningeal Neoplasms
  • Meningioma

Identity

Scopus Document Identifier

  • 85129794981

Digital Object Identifier (DOI)

  • 10.3171/2019.3.FOCUS1971

PubMed ID

  • 35546384

Additional Document Info

volume

  • 158

issue

  • 3