In Search of the Optimal Antithrombotic Regimen for Intracerebral Hemorrhage Survivors with Atrial Fibrillation. Review uri icon

Overview

abstract

  • Spontaneous intracerebral hemorrhage (ICH) constitutes 10-15% of all strokes, and is a significant cause of mortality and morbidity. Survivors of ICH, especially those with atrial fibrillation (AF), are at risk for both recurrent hemorrhagic and ischemic cerebrovascular events. A conundrum in the field of vascular neurology, neurosurgery, and cardiology has been the decision to initiate or resume versus withhold anticoagulation in survivors of ICH with AF. To initiate anticoagulation would decrease the risk of ischemic stroke but may increase the risk of hemorrhage. To withhold anticoagulation maintains a lower risk of hemorrhage but does not decrease the risk of ischemic stroke. In this narrative review, we discuss the evidence for and against the use of antithrombotics in ICH survivors with AF, focusing on recently completed and ongoing clinical trials.

publication date

  • June 3, 2022

Research

keywords

  • Atrial Fibrillation
  • Ischemic Stroke
  • Stroke

Identity

Scopus Document Identifier

  • 85131577571

Digital Object Identifier (DOI)

  • 10.1007/s40265-022-01729-9

PubMed ID

  • 35657478

Additional Document Info

volume

  • 82

issue

  • 9