Sex and cancer immunotherapy: Current understanding and challenges. Academic Article uri icon

Overview

abstract

  • Recent evidence highlights patients' sex relevance in antitumor immune response through a complex interaction-among hormones, genes, behaviors, and the microbiome-that affects both innate and adaptive immune functions, as well as immune evasion mechanisms. These complex interactions ultimately influence the efficacy and toxicity of immune checkpoint inhibitors in solid tumors.

publication date

  • June 23, 2022

Research

keywords

  • Immunotherapy
  • Neoplasms

Identity

Scopus Document Identifier

  • 85133975164

Digital Object Identifier (DOI)

  • 10.1016/j.ccell.2022.06.005

PubMed ID

  • 35750053

Additional Document Info

volume

  • 40

issue

  • 7