Calreticulin exposure orchestrates innate immunosurveillance. Academic Article uri icon

Overview

abstract

  • Calreticulin (CALR) exposure on the cell surface is known to deliver robust pro-phagocytic signals to myeloid cells. In Nature, Sen Santara et al. demonstrate that surface-exposed CALR also operates as an endogenous activator of natural killer (NK) cells. Collectively, these findings suggest that CALR exposure orchestrates multiple facets of innate immunosurveillance.

publication date

  • May 18, 2023

Research

keywords

  • Calreticulin
  • Myeloid Cells

Identity

Scopus Document Identifier

  • 85161073877

Digital Object Identifier (DOI)

  • 10.1016/j.ccell.2023.04.015

PubMed ID

  • 37207656

Additional Document Info

volume

  • 41

issue

  • 6