Unilateral vs. bilateral retinoblastoma. Correlations between age at diagnosis and stage of ocular disease. Academic Article uri icon

Overview

abstract

  • Retrospective analysis of 358 cases of retinoblastoma for correlation between age and intraocular stage at the time of diagnosis revealed: in both early and advanced stages of intraocular disease, bilateral retinoblastoma presents at an earlier age than does unilateral retinoblastoma; support for the Knudson "two-hit" hypothesis of retinoblastoma genetics, the existence of a positive family history for retinoblastoma does not guarantee an earlier age at diagnosis compared to sporadic disease; and for any age at diagnosis, unilateral or bilateral disease, Group V is the most common intraocular stage found.

publication date

  • August 1, 1986

Research

keywords

  • Eye Neoplasms
  • Retinoblastoma

Identity

Scopus Document Identifier

  • 0022548425

Digital Object Identifier (DOI)

  • 10.1016/s0161-6420(86)33629-7

PubMed ID

  • 3763146

Additional Document Info

volume

  • 93

issue

  • 8