The helical hydrophobic moment avoids prolines in phospholipid-binding proteins.
Academic Article
Overview
abstract
Proline residues appear to punctuate the distribution of amphiphilic phospholipid-binding regions of apolipoproteins. We have applied a quantitative test to this hypothesis and shown that the magnitude of the helical hydrophobic moment around proline residues is reduced in lipid-binding proteins and peptides.
