Rapid amino acid uptake in rat pituitary neural lobe during functional stimulation by chronic dehydration. Academic Article uri icon

Overview

abstract

  • We studied the transfer of a small neutral amino acid, alpha-aminoisobutyric acid, from arterial blood into the pituitary neural lobe in normal rats and in rats deprived of water for 5 days. A threefold increase in the neural lobe uptake of the amino acid was found in the chronically dehydrated rats. Possible causes for this effect include enlargement of the capillary and pituicyte membrane surface areas available for solute flux and increased permeability of these membranes. Such functional and structural alterations may be associated with an increase in protein turnover in the neural lobe during dehydration.

publication date

  • March 1, 1985

Research

keywords

  • Aminoisobutyric Acids
  • Dehydration
  • Pituitary Gland

Identity

Scopus Document Identifier

  • 0021925740

Digital Object Identifier (DOI)

  • 10.1038/jcbfm.1985.19

PubMed ID

  • 3972918

Additional Document Info

volume

  • 5

issue

  • 1