Iodine toxicity in a patient treated by continuous povidone-iodine mediastinal irrigation. uri icon

Overview

abstract

  • Continuous povidone-iodine irrigation is frequently used to treat mediastinitis after median sternotomy and has been considered safe and effective. We describe a 34-month-old patient with mediastinitis after median sternotomy who was treated with continuous povidone-iodine irrigation and who absorbed toxic quantities of iodine (total serum iodine, 9,375 micrograms/dl; normal range, 4.5 to 9.0 micrograms/dl). An unexplained metabolic acidosis developed, along with changes in mental status, and the patient died. This experience and a thorough review of the literature lead us to believe that continuous povidone-iodine irrigation of the mediastinum is contraindicated.

publication date

  • May 1, 1985

Research

keywords

  • Iodine
  • Mediastinitis
  • Therapeutic Irrigation

Identity

Scopus Document Identifier

  • 0022245913

Digital Object Identifier (DOI)

  • 10.1016/s0003-4975(10)61965-0

PubMed ID

  • 3994451

Additional Document Info

volume

  • 39

issue

  • 5