Effect of ventricular function on left ventricular ejection time in aortic stenosis. Academic Article uri icon

Overview

abstract

  • Since recognition of factors which modify the duration of ejection in aortic stenosis is of clinical importance, the relations among rate-corrected left ventricular ejection time, aortic valve area, and determinants of ventricular performance were studied in 54 catheterised patients. In patients with a normal cardiac index, increasing duration of ejection was linearly related to increasing obstruction. In patients with failing ventricles, on the other hand, the ejection time was less prolonged, and the duration of ejection was unrelated to valve area. At fixed valve area, relation with cardiac output, stroke volume, heart rate, mean aortic valve pressure gradient, mean aortic pressure, and left ventricular end-diastolic pressure could not adequately explain the observed scatter in ejection time. This suggests a multifactorial basis for the wide range of ejection times observed with severe aortic stenosis.

publication date

  • October 1, 1979

Research

keywords

  • Aortic Valve Stenosis
  • Heart Ventricles
  • Myocardial Contraction

Identity

PubMed Central ID

  • PMC482179

Scopus Document Identifier

  • 0018693594

Digital Object Identifier (DOI)

  • 10.1136/hrt.42.4.438

PubMed ID

  • 508475

Additional Document Info

volume

  • 42

issue

  • 4