Glutaraldehyde-preserved pericardial allografts for pericardial closure. Academic Article uri icon

Overview

abstract

  • Repeat cardiac surgery is significantly more difficult than the original surgery. Pericardial closure to limit adhesion formation between the heart and mediastinal structures and thus reduce the increased difficulty of reoperation has been considered. To investigate the feasibility of effecting loose pericardial closure with homologous pericardial grafts, glutaraldehyde-preserved pericardial allografts were implanted in 10 mongrel dogs. After a mean period of 6.7 months (range 6 to 8 months) the grafts were studied grossly and histologically. Adhesion formation was minimal and the adhesions were easily dissectible. The allografts evoked no significant inflammatory response. No infections resulted from graft placement. It is concluded that glutaraldehyde-preserved pericardial allografts may be useful to effect pericardial closure and deserve further investigation in this regard.

publication date

  • January 1, 1984

Research

keywords

  • Pericardium

Identity

Scopus Document Identifier

  • 0021366992

Digital Object Identifier (DOI)

  • 10.1016/0022-4804(84)90066-0

PubMed ID

  • 6418973

Additional Document Info

volume

  • 36

issue

  • 1